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Labeling of DOTA-conjugated HPMA-based polymers with trivalent metallic radionuclides for molecular imaging
BACKGROUND: In this work, the in vitro and in vivo stabilities and the pharmacology of HPMA-made homopolymers were studied by means of radiometal-labeled derivatives. Aiming to identify the fewer amount and the optimal DOTA-linker structure that provides quantitative labeling yields, diverse DOTA-li...
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| izdano v: | EJNMMI Res |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Springer Berlin Heidelberg
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5829281/ https://ncbi.nlm.nih.gov/pubmed/29488030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-018-0372-x |
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