Improved radiolabeling of DOTATOC with trivalent radiometals for clinical application by addition of ethanol

BACKGROUND: Typically, metal-based radiopharmaceuticals are synthesized in aqueous solutions with no or low ethanol content. Labeling yields are defined by temperature, period of labeling, amount of precursor, pH etc. As recently observed, radiolabeling yields (RCY) seem to increase in the presence...

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Bibliografiske detaljer
Udgivet i:EJNMMI Radiopharm Chem
Main Authors: Eppard, Elisabeth, Pèrez-Malo, Marylaine, Rösch, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Springer International Publishing 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5843808/
https://ncbi.nlm.nih.gov/pubmed/29564383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41181-016-0010-8
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