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Key Inflammatory Processes in Human NASH Are Reflected in Ldlr(−/−).Leiden Mice: A Translational Gene Profiling Study

Introduction: It is generally accepted that metabolic inflammation in the liver is an important driver of disease progression in NASH and associated matrix remodeling/fibrosis. However, the exact molecular inflammatory mechanisms are poorly defined in human studies. Investigation of key pathogenic m...

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Pubblicato in:Front Physiol
Autori principali: Morrison, Martine C., Kleemann, Robert, van Koppen, Arianne, Hanemaaijer, Roeland, Verschuren, Lars
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5829089/
https://ncbi.nlm.nih.gov/pubmed/29527177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2018.00132
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