Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model

BACKGROUND & AIMS: The incidence of nonalcoholic steatohepatitis (NASH) is increasing. The pathophysiological mechanisms of NASH and the sequence of events leading to hepatic fibrosis are incompletely understood. The aim of this study was to gain insight into the dynamics of key molecular proces...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: van Koppen, Arianne, Verschuren, Lars, van den Hoek, Anita M., Verheij, Joanne, Morrison, Martine C., Li, Kelvin, Nagabukuro, Hiroshi, Costessi, Adalberto, Caspers, Martien P.M., van den Broek, Tim J., Sagartz, John, Kluft, Cornelis, Beysen, Carine, Emson, Claire, van Gool, Alain J., Goldschmeding, Roel, Stoop, Reinout, Bobeldijk-Pastorova, Ivana, Turner, Scott M., Hanauer, Guido, Hanemaaijer, Roeland
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738456/
https://ncbi.nlm.nih.gov/pubmed/29276754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.10.001
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