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Lysosomal Enzyme Replacement Therapies: Historical Development, Clinical Outcomes, and Future Perspectives
Lysosomes and lysosomal enzymes play a central role in numerous cellular processes, including cellular nutrition, recycling, signaling, defense, and cell death. Genetic deficiencies of lysosomal components, most commonly enzymes, are known as “lysosomal storage disorders” or “lysosomal diseases” (LD...
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| Publicado no: | Adv Drug Deliv Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828774/ https://ncbi.nlm.nih.gov/pubmed/28502768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2017.05.004 |
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