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Naked mole rats can undergo developmental, oncogene-induced and DNA damage-induced cellular senescence

Cellular senescence is an important anticancer mechanism that restricts proliferation of damaged or premalignant cells. Cellular senescence also plays an important role in tissue remodeling during development. However, there is a trade-off associated with cellular senescence as senescent cells contr...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Zhao, Yang, Tyshkovskiy, Alexander, Muñoz-Espín, Daniel, Tian, Xiao, Serrano, Manuel, de Magalhaes, Joao Pedro, Nevo, Eviatar, Gladyshev, Vadim N., Seluanov, Andrei, Gorbunova, Vera
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828632/
https://ncbi.nlm.nih.gov/pubmed/29432174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1721160115
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