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Damaging de novo mutations diminish motor skills in children on the autism spectrum

In individuals with autism spectrum disorder (ASD), de novo mutations have previously been shown to be significantly correlated with lower IQ but not with the core characteristics of ASD: deficits in social communication and interaction and restricted interests and repetitive patterns of behavior. W...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Buja, Andreas, Volfovsky, Natalia, Krieger, Abba M., Lord, Catherine, Lash, Alex E., Wigler, Michael, Iossifov, Ivan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828599/
https://ncbi.nlm.nih.gov/pubmed/29434036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715427115
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