Capicua controls Toll/IL-1 signaling targets independently of RTK regulation

The HMG-box protein Capicua (Cic) is a conserved transcriptional repressor that functions downstream of receptor tyrosine kinase (RTK) signaling pathways in a relatively simple switch: In the absence of signaling, Cic represses RTK-responsive genes by binding to nearly invariant sites in DNA, wherea...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Papagianni, Aikaterini, Forés, Marta, Shao, Wanqing, He, Shuonan, Koenecke, Nina, Andreu, María José, Samper, Núria, Paroush, Ze’ev, González-Crespo, Sergio, Zeitlinger, Julia, Jiménez, Gerardo
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828586/
https://ncbi.nlm.nih.gov/pubmed/29432195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713930115
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