RTK signaling modulates the Dorsal gradient

The dorsoventral (DV) axis of the Drosophila embryo is patterned by a nuclear gradient of the Rel family transcription factor, Dorsal (Dl), that activates or represses numerous target genes in a region-specific manner. Here, we demonstrate that signaling by receptor tyrosine kinases (RTK) reduces nu...

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Autori principali: Helman, Aharon, Lim, Bomyi, Andreu, María José, Kim, Yoosik, Shestkin, Tatyana, Lu, Hang, Jiménez, Gerardo, Shvartsman, Stanislav Y., Paroush, Ze’ev
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2012
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Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403108/
https://ncbi.nlm.nih.gov/pubmed/22791891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.075812
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