LRRK2 mediated Rab8a phosphorylation promotes lipid storage

BACKGROUND: Several mutations in leucine rich repeat kinase 2 (LRRK2) gene have been associated with pathogenesis of Parkinson’s disease (PD), a neurodegenerative disorder marked by resting tremors, and rigidity, leading to Postural instability. It has been revealed that mutations that lead to an in...

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Bibliografiske detaljer
Udgivet i:Lipids Health Dis
Main Authors: Yu, Miao, Arshad, Muhammad, Wang, Wenmin, Zhao, Dongyu, Xu, Li, Zhou, Linkang
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828482/
https://ncbi.nlm.nih.gov/pubmed/29482628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0684-x
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