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The degree of enhancer or promoter activity is reflected by the levels and directionality of eRNA transcription

Gene expression is regulated by promoters, which initiate transcription, and enhancers, which control their temporal and spatial activity. However, the discovery that mammalian enhancers also initiate transcription questions the inherent differences between enhancers and promoters. Here, we investig...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Mikhaylichenko, Olga, Bondarenko, Vladyslav, Harnett, Dermot, Schor, Ignacio E., Males, Matilda, Viales, Rebecca R., Furlong, Eileen E.M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828394/
https://ncbi.nlm.nih.gov/pubmed/29378788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.308619.117
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