Tumour vasculature immaturity, oxidative damage and systemic inflammation stratify survival of colorectal cancer patients on bevacizumab treatment

Despite treatment of patients with metastatic colorectal cancer (mCRC) with bevacizumab plus chemotherapy, response rates are modest and there are no biomarkers available that will predict response. The aim of this study was to assess if markers associated with three interconnected cancer-associated...

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Pubblicato in:Oncotarget
Autori principali: Noonan, Sinead A., Morrissey, Maria E., Martin, Petra, Biniecka, Monika, Ó'Meachair, Shane, Maguire, Aoife, Tosetto, Miriam, Nolan, Blathnaid, Hyland, John, Sheahan, Kieran, O'Donoghue, Diarmuid, Mulcahy, Hugh, Fennelly, David, O'Sullivan, Jacintha
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828217/
https://ncbi.nlm.nih.gov/pubmed/29535825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24276
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