Transcription factors Tp73, Cebpd, Pax6, and Spi1 rather than DNA methylation regulate chronic transcriptomics changes after experimental traumatic brain injury

Traumatic brain injury (TBI) induces a wide variety of cellular and molecular changes that can continue for days to weeks to months, leading to functional impairments. Currently, there are no pharmacotherapies in clinical use that favorably modify the post-TBI outcome, due in part to limited underst...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Lipponen, Anssi, El-Osta, Assam, Kaspi, Antony, Ziemann, Mark, Khurana, Ishant, KN, Harikrishnan, Navarro-Ferrandis, Vicente, Puhakka, Noora, Paananen, Jussi, Pitkänen, Asla
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828078/
https://ncbi.nlm.nih.gov/pubmed/29482641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-018-0519-z
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