Structure of the yeast spliceosomal post-catalytic P complex

The spliceosome undergoes dramatic changes in a splicing cycle. Structures of B, B(act), C, C*, and ILS complexes revealed mechanisms of 5′ splice site (ss) recognition, branching, and intron release, but lacked information on 3′ ss recognition, exon ligation and release. Here, we report a cryoEM st...

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Publicado en:Science
Main Authors: Liu, Shiheng, Li, Xueni, Zhang, Lingdi, Jiang, Jiansen, Hill, Ryan C., Cui, Yanxiang, Hansen, Kirk C., Zhou, Z. Hong, Zhao, Rui
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828012/
https://ncbi.nlm.nih.gov/pubmed/29146870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar3462
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