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Recombinant cells in the lung increase with age via de novo recombination events and clonal expansion
Homologous recombination (HR) is a critical DNA repair pathway, which is usually error-free, but can sometimes lead to cancer-promoting mutations. Despite the importance of HR as a driver of mutations, the spontaneous frequency of such mutations has proven difficult to study. In order to gain insigh...
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| Publicat a: | Environ Mol Mutagen |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5827959/ https://ncbi.nlm.nih.gov/pubmed/28370323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/em.22082 |
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