Rosa26-GFP Direct Repeat (RaDR-GFP) Mice Reveal Tissue- and Age-Dependence of Homologous Recombination in Mammals In Vivo

Homologous recombination (HR) is critical for the repair of double strand breaks and broken replication forks. Although HR is mostly error free, inherent or environmental conditions that either suppress or induce HR cause genomic instability. Despite its importance in carcinogenesis, due to limitati...

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Main Authors: Sukup-Jackson, Michelle R., Kiraly, Orsolya, Kay, Jennifer E., Na, Li, Rowland, Elizabeth A., Winther, Kelly E., Chow, Danielle N., Kimoto, Takafumi, Matsuguchi, Tetsuya, Jonnalagadda, Vidya S., Maklakova, Vilena I., Singh, Vijay R., Wadduwage, Dushan N., Rajapakse, Jagath, So, Peter T. C., Collier, Lara S., Engelward, Bevin P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046920/
https://ncbi.nlm.nih.gov/pubmed/24901438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004299
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