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Inflammation-induced cell proliferation potentiates DNA damage-induced mutations in vivo.
Mutations are a critical driver of cancer initiation. While extensive studies have focused on exposure-induced mutations, few studies have explored the importance of tissue physiology as a modulator of mutation susceptibility in vivo. Of particular interest is inflammation, a known cancer risk facto...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2015-02-01
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| Colecção: | PLoS Genetics |
| Acesso em linha: | http://europepmc.org/articles/PMC4372043?pdf=render |
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