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Continuous multistep synthesis of 2-(azidomethyl)oxazoles
An efficient three-step protocol was developed to produce 2-(azidomethyl)oxazoles from vinyl azides in a continuous-flow process. The general synthetic strategy involves a thermolysis of vinyl azides to generate azirines, which react with bromoacetyl bromide to provide 2-(bromomethyl)oxazoles. The l...
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| Izdano u: | Beilstein J Org Chem |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Beilstein-Institut
2018
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5827817/ https://ncbi.nlm.nih.gov/pubmed/29520312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.36 |
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