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Palladium-catalyzed ortho-halogenations of acetanilides with N-halosuccinimides via direct sp(2) C–H bond activation in ball mills

A solvent-free palladium-catalyzed ortho-iodination of acetanilides using N-iodosuccinimide as the iodine source has been developed under ball-milling conditions. This present method avoids the use of hazardous organic solvents, high reaction temperature, and long reaction time and provides a highly...

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Publicat a:Beilstein J Org Chem
Autors principals: Liu, Zi, Xu, Hui, Wang, Guan-Wu
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827707/
https://ncbi.nlm.nih.gov/pubmed/29520307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.31
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