Cyclipostins and cyclophostin analogs inhibit the antigen 85C from Mycobacterium tuberculosis both in vitro and in vivo

An increasing prevalence of cases of drug-resistant tuberculosis requires the development of more efficacious chemotherapies. We previously reported the discovery of a new class of cyclipostins and cyclophostin (CyC) analogs exhibiting potent activity against Mycobacterium tuberculosis both in vitro...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Viljoen, Albertus, Richard, Matthias, Nguyen, Phuong Chi, Fourquet, Patrick, Camoin, Luc, Paudal, Rishi R., Gnawali, Giri R., Spilling, Christopher D., Cavalier, Jean-François, Canaan, Stéphane, Blaise, Mickael, Kremer, Laurent
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5827452/
https://ncbi.nlm.nih.gov/pubmed/29301937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.000760
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