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The First Total Synthesis of (±) Cyclophostin and (±) Cyclipostin P: Inhibitors of the Serine Hydrolases Acetyl Cholinesterase and Hormone Sensitive Lipase

[Image: see text] Cyclophostin, a structurally unique and potent naturally occurring acetyl cholinesterase (AChE) inhibitor, and its unnatural diastereomer were prepared in 6 steps and 15% overall yield from hydroxymethyl butyrolactone. The unnatural diastereomer of cyclophostin was converted into c...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Malla, Raj K., Bandyopadhyay, Saibal, Spilling, Christopher D., Dutta, Supratik, Dupureur, Cynthia M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129627/
https://ncbi.nlm.nih.gov/pubmed/21591624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol200991x
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