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The mTOR-S6K Pathway Links Growth Signaling to DNA Damage Response by Targeting RNF168
Growth signals, such as extracellular nutrients and growth factors, have significant impacts on genome integrity, while the direct underlying link remains unclear. Here we show that the mechanistic target of rapamycin (mTOR)-ribosomal S6 kinase (S6K) pathway, a central regulator of growth signaling,...
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| Yayımlandı: | Nat Cell Biol |
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| Asıl Yazarlar: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826806/ https://ncbi.nlm.nih.gov/pubmed/29403037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-017-0033-8 |
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