IFN-γ and tumor gangliosides: implications for the tumor microenvironment

Gangliosides shed by tumors into their microenvironment (TME) are immunoinhibitory. Interferon-γ (IFN-γ) may boost antitumor immune responses. Thus we wondered whether IFN-γ would counteract tumor ganglioside-mediated immune suppression. To test this hypothesis, we exposed human monocyte-derived LPS...

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Publicado no:Cell Immunol
Main Authors: Dillinger, Barbara, Ahmadi-Erber, Sarah, Lau, Manuel, Hoelzl, Markus A, Erhart, Friedrich, Juergens, Birgit, Fuchs, Dietmar, Heitger, Andreas, Ladisch, Stephan, Dohnal, Alexander M
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826801/
https://ncbi.nlm.nih.gov/pubmed/29402391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2018.01.014
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