IFNγ-Dependent Tissue-Immune Homeostasis Is Co-opted in the Tumor Microenvironment

Homeostatic programs balance immune protection and self-tolerance. Such mechanisms likely impact autoimmunity and tumor formation, respectively. How homeostasis is maintained and impacts tumor surveillance is unknown. Here, we find that different immune mononuclear phagocytes share a conserved stead...

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Publicado en:Cell
Main Authors: Nirschl, Christopher J., Suárez-Fariñas, Mayte, Izar, Benjamin, Prakadan, Sanjay, Dannenfelser, Ruth, Tirosh, Itay, Liu, Yong, Zhu, Qian, Devi, K. Sanjana P., Carroll, Shaina L., Chau, David, Rezaee, Melika, Kim, Tae-Gyun, Huang, Ruiqi, Fuentes-Duculan, Judilyn, Song-Zhao, George X., Gulati, Nicholas, Lowes, Michelle A., King, Sandra L., Quintana, Francisco J., Lee, Young-suk, Krueger, James G., Sarin, Kavita Y., Yoon, Charles H., Garraway, Levi, Regev, Aviv, Shalek, Alex K., Troyanskaya, Olga, Anandasabapathy, Niroshana
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569303/
https://ncbi.nlm.nih.gov/pubmed/28666115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.06.016
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