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Polymerization of hexamethylene diisocyanate in solution and a 260.23 m/z [M+H](+) ion in exposed human cells

Hexamethylene diisocyanate (HDI) is an important industrial chemical that can cause asthma, however pathogenic mechanisms remain unclear. Upon entry into the respiratory tract, HDI’s N=C=O groups may undergo nucleophilic addition (conjugate) to host molecules (e.g. proteins), or instead react with w...

詳細記述

保存先:
書誌詳細
出版年:Anal Biochem
主要な著者: Wisnewski, Adam V, Liu, Jian, Redlich, Carrie A, Nassar, Ala F
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826792/
https://ncbi.nlm.nih.gov/pubmed/29175138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2017.11.017
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