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Polymerization of hexamethylene diisocyanate in solution and a 260.23 m/z [M+H](+) ion in exposed human cells
Hexamethylene diisocyanate (HDI) is an important industrial chemical that can cause asthma, however pathogenic mechanisms remain unclear. Upon entry into the respiratory tract, HDI’s N=C=O groups may undergo nucleophilic addition (conjugate) to host molecules (e.g. proteins), or instead react with w...
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| Veröffentlicht in: | Anal Biochem |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826792/ https://ncbi.nlm.nih.gov/pubmed/29175138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2017.11.017 |
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