Loading...
SIRT6 deacetylates H3K18Ac at pericentric chromatin to prevent mitotic errors and cell senescence
Pericentric heterochromatin silencing at mammalian centromeres is essential for mitotic fidelity and genomic stability. Defective pericentric silencing is observed in senescent cells, aging tissues, and mammalian tumors, but the underlying mechanisms and functional consequences of these defects are...
Na minha lista:
| Udgivet i: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2016
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5826646/ https://ncbi.nlm.nih.gov/pubmed/27043296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3202 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|