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Somatic mutations and clonal hematopoiesis: unexpected potential new drivers of age-related cardiovascular disease

Increasing evidence shows that conventional cardiovascular risk factors are incompletely predictive of cardiovascular disease, particularly in elderly individuals, suggesting that there may still be unidentified causal risk factors. While the accumulation of somatic DNA mutations is a hallmark of ag...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Fuster, José J., Walsh, Kenneth
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826570/
https://ncbi.nlm.nih.gov/pubmed/29420212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.117.312115
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