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Genetics of age-related clonal hematopoiesis and atherosclerotic cardiovascular disease

PURPOSE OF REVIEW: While advanced age is the major risk factor for the development of atherosclerotic cardiovascular disease (ASCVD), we have a poor understanding of how aging promotes the progression of this disease. Recent evidence suggests that the age-dependent accumulation of somatic mutations...

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Veröffentlicht in:Curr Opin Cardiol
Hauptverfasser: Jung, Changhee, Evans, Megan A., Walsh, Kenneth
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7138732/
https://ncbi.nlm.nih.gov/pubmed/32073406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HCO.0000000000000726
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