CBP regulates recruitment and release of promoter-proximal RNA polymerase II

Transcription activation involves RNA polymerase II (Pol II) recruitment and release from the promoter into productive elongation, but how specific chromatin regulators control these steps is unclear. Here we identify a novel activity of the histone acetyltransferase p300/CBP in regulating promoter-...

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Gepubliceerd in:Mol Cell
Hoofdauteurs: Boija, Ann, Mahat, Dig Bijay, Zare, Aman, Holmqvist, Per-Henrik, Philip, Philge, Meyers, David J., Cole, Philip A., Lis, John T., Stenberg, Per, Mannervik, Mattias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826544/
https://ncbi.nlm.nih.gov/pubmed/29056321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.031
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