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CBP regulates recruitment and release of promoter-proximal RNA polymerase II

Transcription activation involves RNA polymerase II (Pol II) recruitment and release from the promoter into productive elongation, but how specific chromatin regulators control these steps is unclear. Here we identify a novel activity of the histone acetyltransferase p300/CBP in regulating promoter-...

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Bibliographic Details
Published in:Mol Cell
Main Authors: Boija, Ann, Mahat, Dig Bijay, Zare, Aman, Holmqvist, Per-Henrik, Philip, Philge, Meyers, David J., Cole, Philip A., Lis, John T., Stenberg, Per, Mannervik, Mattias
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826544/
https://ncbi.nlm.nih.gov/pubmed/29056321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.09.031
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