Role of ubenimex as an anticancer drug and its synergistic effect with Akt inhibitor in human A375 and A2058 cells

BACKGROUND: Malignant melanoma (MM) is a malignant tumor produced by changes in melanocytes in the skin or other organs. In the classification of skin tumor mortality, skin melanoma ranks the highest. Ubenimex, an Aminopeptidase N (APN) inhibitor, is now widely used for cancer as an adjunct therapy,...

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Publicat a:Onco Targets Ther
Autors principals: Wang, Xiaoqing, Liu, Yang, Wu, Rongde, Guo, Feng, Zhang, Lijuan, Cui, Mingyu, Wu, Xiangyu, Zhang, Yongfei, Liu, Wei
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5826084/
https://ncbi.nlm.nih.gov/pubmed/29503569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S157480
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