Proton‐independent activation of acid‐sensing ion channel 3 by an alkaloid, lindoldhamine, from Laurus nobilis

BACKGROUND AND PURPOSE: Acid‐sensing ion channels (ASICs) play an important role in synaptic plasticity and learning, as well as in nociception and mechanosensation. ASICs are involved in pain and in neurological and psychiatric diseases, but their therapeutic potential is limited by the lack of lig...

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Enregistré dans:
Détails bibliographiques
Publié dans:Br J Pharmacol
Auteurs principaux: Osmakov, Dmitry I, Koshelev, Sergey G, Andreev, Yaroslav A, Dubinnyi, Maxim A, Kublitski, Vadim S, Efremov, Roman G, Sobolevsky, Alexander I, Kozlov, Sergey A
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825300/
https://ncbi.nlm.nih.gov/pubmed/29277899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14134
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