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microRNA-181a Downregulates Deptor for TGFβ-induced Glomerular Mesangial Cell Hypertrophy and Matrix Protein Expression
TGFβ contributes to mesangial cell hypertrophy and matrix protein increase in various kidney diseases including diabetic nephropathy. Deptor is an mTOR-interacting protein and suppresses mTORC1 and mTORC2 activities. We have recently shown that TGFβ-induced inhibition of deptor increases the mTOR ac...
Tallennettuna:
| Julkaisussa: | Exp Cell Res |
|---|---|
| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5825286/ https://ncbi.nlm.nih.gov/pubmed/29397070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2018.01.021 |
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