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Junction opener protein increases nanoparticle accumulation in solid tumors

Carcinomas contain tight junctions that can limit the penetration and therefore therapeutic efficacy of anticancer agents, especially those delivered by nano-carrier systems. The junction opener (JO) protein is a virus-derived protein that can transiently open intercellular junctions in epithelial t...

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Publicat a:J Control Release
Autors principals: Wang, Christine E., Yumul, Roma C., Lin, Jonathan, Cheng, Yilong, Lieber, André, Pun, Suzie H.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825283/
https://ncbi.nlm.nih.gov/pubmed/29305923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2017.12.032
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