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Elimination of tumor by CD47/PD-L1 dual-targeting fusion protein that engages innate and adaptive immune responses

The host immune system generally serves as a barrier against tumor formation. Programmed death-ligand 1 (PD-L1) is a critical “don't find me” signal to the adaptive immune system, whereas CD47 transmits an anti-phagocytic signal, known as the “don't eat me” signal, to the innate immune sys...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Liu, Boning, Guo, Huaizu, Xu, Jin, Qin, Ting, Guo, Qingcheng, Gu, Nana, Zhang, Dapeng, Qian, Weizhu, Dai, Jianxin, Hou, Sheng, Wang, Hao, Guo, Yajun
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5825205/
https://ncbi.nlm.nih.gov/pubmed/29182441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2017.1409319
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