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Genome-wide association study identifies genetic variants influencing F-cell levels in sickle-cell patients
Fetal hemoglobin (HbF) level has emerged as an important prognostic factor in sickle-cell disease (SCD) and can be measured by the proportion of HbF-containing erythrocytes (F-cells). Recently, BCL11A (zinc-finger protein) was identified as a regulator of HbF, and the strongest association signals w...
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| Izdano u: | J Hum Genet |
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| Glavni autori: | , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5825003/ https://ncbi.nlm.nih.gov/pubmed/21326311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jhg.2011.12 |
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