The JAK2/STAT5 signaling pathway as a potential therapeutic target in canine mastocytoma

BACKGROUND: Mastocytoma are frequently diagnosed cutaneous neoplasms in dogs. In non-resectable mastocytoma patients, novel targeted drugs are often applied. The transcription factor STAT5 has been implicated in the survival of human neoplastic mast cells (MC). Our study evaluated the JAK2/STAT5 pat...

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Udgivet i:Vet Comp Oncol
Main Authors: Keller, Alexandra, Wingelhofer, Bettina, Peter, Barbara, Bauer, Karin, Berger, Daniela, Gamperl, Susanne, Reifinger, Martin, Cerny-Reiterer, Sabine, Moriggl, Richard, Willmann, Michael, Valent, Peter, Hadzijusufovic, Emir
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824979/
https://ncbi.nlm.nih.gov/pubmed/28397975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/vco.12311
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