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Hypothalamic loss of Snord116 and Prader-Willi syndrome hyperphagia: the buck stops here?

Hyperphagia and obesity are the best-known manifestations of Prader-Willi syndrome (PWS) and are responsible for most of the overall morbidity and mortality associated with the disease. Yet these PWS symptoms remain poorly understood and without effective pharmacologic therapies. Mouse models attemp...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Rodriguez, Juan A., Zigman, Jeffrey M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824859/
https://ncbi.nlm.nih.gov/pubmed/29376891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99725
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