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Hypothalamic loss of Snord116 and Prader-Willi syndrome hyperphagia: the buck stops here?
Hyperphagia and obesity are the best-known manifestations of Prader-Willi syndrome (PWS) and are responsible for most of the overall morbidity and mortality associated with the disease. Yet these PWS symptoms remain poorly understood and without effective pharmacologic therapies. Mouse models attemp...
Enregistré dans:
| Publié dans: | J Clin Invest |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5824859/ https://ncbi.nlm.nih.gov/pubmed/29376891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99725 |
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