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Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective

High-throughput screening (HTS) is a proven method for discovering new lead matter for drug discovery and chemical biology. To maximize the likelihood of identifying genuine binders to a molecular target, and avoid wasting resources following up compounds with unproductive/nonspecific mechanisms of...

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Dettagli Bibliografici
Pubblicato in:SLAS Discov
Autori principali: Rainard, Julie M., Pandarakalam, George C., McElroy, Stuart P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824829/
https://ncbi.nlm.nih.gov/pubmed/29460707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217744728
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