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Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective
High-throughput screening (HTS) is a proven method for discovering new lead matter for drug discovery and chemical biology. To maximize the likelihood of identifying genuine binders to a molecular target, and avoid wasting resources following up compounds with unproductive/nonspecific mechanisms of...
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| Publicado en: | SLAS Discov |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
SAGE Publications
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5824829/ https://ncbi.nlm.nih.gov/pubmed/29460707 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217744728 |
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