An Automated Microscale Thermophoresis Screening Approach for Fragment-Based Lead Discovery

Fragment-based lead discovery has proved to be an effective alternative to high-throughput screenings in identifying chemical matter that can be developed into robust lead compounds. The search for optimal combinations of biophysical techniques that can correctly and efficiently identify and quantif...

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Bibliographic Details
Published in:J Biomol Screen
Main Authors: Linke, Pawel, Amaning, Kwame, Maschberger, Melanie, Vallee, Francois, Steier, Valerie, Baaske, Philipp, Duhr, Stefan, Breitsprecher, Dennis, Rak, Alexey
Format: Artigo
Language:Inglês
Published: SAGE Publications 2015
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Technical Notes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4800460/
https://ncbi.nlm.nih.gov/pubmed/26637553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057115618347
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