ACE2‐EPC‐EXs protect ageing ECs against hypoxia/reoxygenation‐induced injury through the miR‐18a/Nox2/ROS pathway

Oxidative stress is one of the mechanisms of ageing‐associated vascular dysfunction. Angiotensin‐converting enzyme 2 (ACE2) and microRNA (miR)‐18a have shown to be down‐regulated in ageing cells. Our previous study has shown that ACE2‐primed endothelial progenitor cells (ACE2‐EPCs) have protective e...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhang, Cheng, Wang, Jinju, Ma, Xiaotang, Wang, Wenjun, Zhao, Bin, Chen, Yanfang, Chen, Can, Bihl, Ji C.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824419/
https://ncbi.nlm.nih.gov/pubmed/29363860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13471
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