Neuronal Over-expression of ACE2 Protects Brain from Ischemia-induced Damage

Angiotensin (Ang) II exaggerates cerebral injury in ischemic damage. Angiotensin-converting enzyme type 2 (ACE2) converts Ang II into Ang (1–7) and thus, may protect against the effects of Ang II. We hypothesized that neuronal ACE2 over-expression decreases ischemic stroke in mice with Ang II overpr...

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Main Authors: Chen, Ji, Zhao, Yuhui, Chen, Shuzhen, Wang, Jinju, Xiao, Xiang, Ma, Xiaotang, Penchikala, Madhuri, Xia, Huijing, Lazartigues, Eric, Zhao, Bin, Chen, Yanfang
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3992949/
https://ncbi.nlm.nih.gov/pubmed/24440367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2014.01.004
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