Angiotensin-(1-7) Counteracts Angiotensin II-induced Dysfunction in Cerebral Endothelial Cells via Modulating Nox2/ROS and PI3K/NO Pathways

Angiotensin (Ang) II, the main effector of the renin-angiotensin system, has been implicated in the pathogenesis of vascular diseases. Ang-(1-7) binds to the G protein-coupled Mas receptor (MasR) and can exert vasoprotective effects. We investigated the effects and underlying mechanisms of Ang-(1-7)...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Xiao, Xiang, Zhang, Cheng, Ma, Xiaotang, Miao, Huilai, Wang, Jinju, Liu, Langni, Chen, Shuzhen, Zeng, Rong, Chen, Yanfang, Bihl, Ji C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509813/
https://ncbi.nlm.nih.gov/pubmed/26101159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2015.06.010
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