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Examining tRNA 3′-ends in Escherichia coli: teamwork between CCA-adding enzyme, RNase T, and RNase R

tRNA maturation and quality control are crucial for proper functioning of these transcripts in translation. In several organisms, defective tRNAs were shown to be tagged by poly(A) or CCACCA tails and subsequently degraded by 3′-exonucleases. In a deep-sequencing analysis of tRNA 3′-ends, we detecte...

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Detaylı Bibliyografya
Yayımlandı:RNA
Asıl Yazarlar: Wellner, Karolin, Czech, Andreas, Ignatova, Zoya, Betat, Heike, Mörl, Mario
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Cold Spring Harbor Laboratory Press 2018
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824355/
https://ncbi.nlm.nih.gov/pubmed/29180590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064436.117
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