Mismatch Repair Deficiency, Microsatellite Instability, and Survival: An Exploratory Analysis of the Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) Trial

IMPORTANCE: Mismatch repair (MMR) deficiency (MMRD) and microsatellite instability (MSI) are prognostic for survival in many cancers and for resistance to fluoropyrimidines in early colon cancer. However, the effect of MMRD and MSI in curatively resected gastric cancer treated with perioperative che...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Smyth, Elizabeth C., Wotherspoon, Andrew, Peckitt, Clare, Gonzalez, David, Hulkki-Wilson, Sanna, Eltahir, Zakaria, Fassan, Matteo, Rugge, Massimo, Valeri, Nicola, Okines, Alicia, Hewish, Madeleine, Allum, William, Stenning, Sally, Nankivell, Matthew, Langley, Ruth, Cunningham, David
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2017
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824280/
https://ncbi.nlm.nih.gov/pubmed/28241187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.6762
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