Mismatch Repair Deficiency, Microsatellite Instability, and Survival: An Exploratory Analysis of the Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) Trial

IMPORTANCE: Mismatch repair (MMR) deficiency (MMRD) and microsatellite instability (MSI) are prognostic for survival in many cancers and for resistance to fluoropyrimidines in early colon cancer. However, the effect of MMRD and MSI in curatively resected gastric cancer treated with perioperative che...

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Bibliografiske detaljer
Udgivet i:JAMA Oncol
Main Authors: Smyth, Elizabeth C., Wotherspoon, Andrew, Peckitt, Clare, Gonzalez, David, Hulkki-Wilson, Sanna, Eltahir, Zakaria, Fassan, Matteo, Rugge, Massimo, Valeri, Nicola, Okines, Alicia, Hewish, Madeleine, Allum, William, Stenning, Sally, Nankivell, Matthew, Langley, Ruth, Cunningham, David
Format: Artigo
Sprog:Inglês
Udgivet: American Medical Association 2017
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5824280/
https://ncbi.nlm.nih.gov/pubmed/28241187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2016.6762
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