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Single-molecule theory of enzymatic inhibition
The classical theory of enzymatic inhibition takes a deterministic, bulk based approach to quantitatively describe how inhibitors affect the progression of enzymatic reactions. Catalysis at the single-enzyme level is, however, inherently stochastic which could lead to strong deviations from classica...
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| Опубликовано в: : | Nat Commun |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group UK
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5823943/ https://ncbi.nlm.nih.gov/pubmed/29472579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02995-6 |
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