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Role of substrate unbinding in Michaelis–Menten enzymatic reactions
The Michaelis–Menten equation provides a hundred-year-old prediction by which any increase in the rate of substrate unbinding will decrease the rate of enzymatic turnover. Surprisingly, this prediction was never tested experimentally nor was it scrutinized using modern theoretical tools. Here we sho...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3970482/ https://ncbi.nlm.nih.gov/pubmed/24616494 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318122111 |
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