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Role of substrate unbinding in Michaelis–Menten enzymatic reactions

The Michaelis–Menten equation provides a hundred-year-old prediction by which any increase in the rate of substrate unbinding will decrease the rate of enzymatic turnover. Surprisingly, this prediction was never tested experimentally nor was it scrutinized using modern theoretical tools. Here we sho...

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Detalhes bibliográficos
Main Authors: Reuveni, Shlomi, Urbakh, Michael, Klafter, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970482/
https://ncbi.nlm.nih.gov/pubmed/24616494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318122111
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