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Single-molecule theory of enzymatic inhibition

The classical theory of enzymatic inhibition takes a deterministic, bulk based approach to quantitatively describe how inhibitors affect the progression of enzymatic reactions. Catalysis at the single-enzyme level is, however, inherently stochastic which could lead to strong deviations from classica...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Robin, Tal, Reuveni, Shlomi, Urbakh, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5823943/
https://ncbi.nlm.nih.gov/pubmed/29472579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-02995-6
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